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Yes, Johnsongrass is a hard weed to kill. It has the ability to grow fast and spread even quicker, so it requires a detailed plan and thorough application to eliminate it. The best plan of action is to kill Johnsongrass while the weed is establishing itself by hiring a lawn care professional or following the steps above. 

Very carefully. You should be cautious when using any of the above methods, as any one of them could lead to you accidentally killing desired grasses and plants. However, there are selective herbicides that can target certain plants over others. Look for a product that only affects the type of weeds you want to eliminate and spares the plants you want to keep.

You should add 1 to 4 inches of mulch, depending on your garden type and needs. Keep in mind that no amount of mulch can completely prevent weeds, but a heavier coverage (closer to 4 inches) can suppress weeds enough that you are only seeing them sprout every few weeks. Finer mulch prevents weeds more effectively than large mulch, so if you’re using mulched leaves or shredded bark, 1 to 2 inches will likely suffice, while 3 to 4 inches is best for larger mulch, like bark chips or straw.

Whether a one-time spray treatment to control mosquitoes is enough depends on multiple factors. Often, you’ll notice a big difference after one application. However, mosquitoes are likely to return if you don't reduce attractive standing water habitats. This usually takes four to eight weeks if it’s still prime mosquito season.