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An active cleaning agent and a drain snake is the best way to clean a main sewer line. You can purchase a regular or enzyme drain cleaner or make a DIY drain cleaner with baking soda. Use your chosen solution at least once a month or as needed to keep your sewer line clear. 

Yes, chemical drain cleaners contain sulfuric acid and hydrochloric acid, both of which are not only dangerous to your health but also extremely caustic. Drain cleaners will corrode your pipes and could lead to destroyed drain lines, especially if the chemicals interact with the piping for long periods. Unfortunately, this extended interaction is likely if you’re dealing with a clog, as the drain cleaner will have just as much trouble as water does moving through your plumbing system.

The cost to unclog a drain varies based on the location and severity of the clog. For simple clogs within your home, such as in a sink, toilet, or shower, hiring a plumber typically costs between $110 and $350, with an average of around $200. Snaking a toilet or sink usually costs between $110 and $275, while a bathtub or shower clog costs about $225.

For a more serious clog in the main sewer line, the cost is higher. Clearing a main line clog generally costs between $200 and $600, with an average of about $380. However, prices can range from as low as $100 for snaking a minor clog to over $1,600, particularly if advanced methods like video inspection and hydrojetting are needed for a large or hard-to-reach blockage. Some severe main line clogs can cost upwards of $1,000 to clear depending on factors like the cause of the clog, its distance from an accessible cleanout, and whether the pipe is located beneath an occupied space (e.g., in an apartment building). You may be able to save money on minor clogs by using a drain snake or bladder yourself.

There are several homemade solutions for clearing a clogged sink that don’t involve pouring harsh chemicals down your drain. Start by pouring hot (but not boiling) water down the drain. This can help dissolve and flush away grease and gunk. A splash of dish soap down the drain can also cut through fat and make it easier to clear the drain. For a more stubborn blockage, grab a plunger and give it a few firm pumps to dislodge the clog.