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Spraying for ticks does a good job of eliminating the existing ticks in your yard. Moderate to severe infestations might require several treatment sessions, but most infestations are well controlled with enough treatments, regardless of their severity.

However, wildlife, pets, and people can still carry ticks into a yard, even after treatment, so if you're concerned about ticks in your area, it's a good idea to spray annually for tick prevention.

A strong honeybee colony can usually fight off the aggressive presence of yellow jackets. However, weaker honeybee colonies with fewer workers are especially vulnerable to yellow jackets. If yellow jackets gain entry into a weakened honeybee colony, they can easily kill the honeybees and empty the hive of all its contents. 

You can easily find sprays that claim they are safe for pets and kids. However, we’d rather not use them in our own homes if we’re worried about pet safety: They still include pesticides and other chemicals, and are best avoided in any food prep areas like the kitchen, or any spots where children and pets may place. That’s why sprays didn’t end up in our suggestions for the safest options.

Squirrels rely heavily on their sense of smell and are deterred by a variety of scents. Some of the most effective smells for repelling them include peppermint oil, coffee grounds, white vinegar, garlic, cinnamon, rosemary, and predator urine. They also have a strong aversion to capsaicin, the compound that makes chili peppers hot, making capsaicin-based sprays an effective repellent for areas like gardens or bird feeders. For a DIY solution, you can create a spray from garlic and vinegar and apply it daily. Additionally, squirrels dislike strong, fresh scents, so placing items like strong-smelling soaps or dryer sheets in areas they frequent can also help keep them away.