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Glyphosate and other non-selective herbicides can kill orchard grass, but they will also kill the surrounding plants. Also, not all areas allow the use of glyphosate due to its environmental impact—which the EPA describes as a "potential risk to terrestrial and aquatic plants and birds, and low toxicity to honeybees." Consider mechanical removal to target the plants specifically.

A spot herbicide for weed control is effective at killing crabgrass and not grass, but it depends on the type of herbicide. Always check the label to ensure that your herbicide is safe for grass but tough on crabgrass. Overall, spot treatment is ideal because it puts fewer herbicides into the soil, which can damage the soil. If you’re wanting a natural remedy to crabgrass that also won’t harm surrounding grass, you can also hand-remove crabgrass or even pour boiling water or 5% vinegar over crabgrass as a spot treatment.

Weeds may grow back when pulled out if the root is not completely removed. Invasive weeds can regrow from just a small portion of remaining root, so using a weed-pulling tool can help ensure you remove the entire root. Weeds may grow back faster if roots aren’t fully removed, and incomplete removal could cause them to spread as well.

Weed control applications usually cost around $100 each for a standard-size yard, and most professionals charge between $30 and $60 per hour for manual weed removal. Your total is affected most by the size of the weeded area. Some weed service companies offer weed control treatments, selective herbicide spraying, and manual removal and upkeep as part of a package, costing around $600 annually. You might pay less if you hire the same company for other lawn services, like flower bed upkeep, aeration, overseeding, and pesticide application.