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You can remove groundhogs yourself using a DIY approach of rags soaked in ammonia, or you can purchase and set a trap for the groundhog. These low-cost methods are easy to implement, but you should ensure that you comply with local laws and regulations concerning animal trapping and release. You can also hire an experienced professional to remove groundhogs from your yard.

What you should do with an armadillo after you catch it depends on what your local laws dictate. Often, it's easiest to relocate an armadillo rather than euthanize it. Contact your local wildlife control office or experts for information specific to your area. After removal is complete, be sure to repair any holes left in your yard or under your home.

While possums don’t typically carry rabies, they can have lice, fleas, ticks, and mites. According to the University of California’s Pest Management Program, possums can also carry diseases like leptospirosis, tuberculosis, toxoplasmosis, coccidiosis, and fevers. Possums are also the carriers of a parasite that can pass to horses and cats called Equine Protozoal Myeloencephalitis (EPM).

It’s very rare to find mice in a bed frame or mattress outside of the most extreme infestation scenarios. That said, your bedroom isn’t off limits for mice if it offers them shelter, food, and warmth. Look for any gaps or openings a mouse could squeeze into, and don’t keep food in your bedroom.