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Squirrels have a strong sense of smell and can be deterred by various scents they dislike. Effective options include peppermint oil, rosemary, garlic, cinnamon, white vinegar, coffee grounds, and predator urine. Squirrels also have a strong aversion to capsaicin, the compound that makes chili peppers hot, making capsaicin-based repellents a good choice for protecting specific areas like gardens or bird feeders. For a DIY solution, you can create a garlic and vinegar spray and apply it daily. Additionally, placing strong-smelling items like certain soaps or dryer sheets near where squirrels frequent can also be effective.

To keep animals out, you must prevent them from entering. As long as they can get in, the problem will persist. That said, consider making your attic less inviting using deterrents like motion-activated lights or ultrasonic devices. Additionally, keeping a well-maintained, clean, and uncluttered attic that you regularly inspect for activity may make the space less attractive to critters.

No, poison isn’t the best way to deal with animals in your attic. It’s unlikely to completely eradicate the problem, especially if you don’t take care of access points. Also, poisoned animals may die and decay in the attic, causing noxious odors. 

Some animals may leave the attic before the poison kills them, which could lead to nearby pets or other wildlife eating the animals and becoming poisoned themselves. Ultimately, it’s better to avoid using poison and contact a professional instead.

While possums don’t typically carry rabies, they can have lice, fleas, ticks, and mites. According to the University of California’s Pest Management Program, possums can also carry diseases like leptospirosis, tuberculosis, toxoplasmosis, coccidiosis, and fevers. Possums are also the carriers of a parasite that can pass to horses and cats called Equine Protozoal Myeloencephalitis (EPM).