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Glyphosate and other non-selective herbicides can kill orchard grass, but they will also kill the surrounding plants. Also, not all areas allow the use of glyphosate due to its environmental impact—which the EPA describes as a "potential risk to terrestrial and aquatic plants and birds, and low toxicity to honeybees." Consider mechanical removal to target the plants specifically.

The safest method to avoid killing your turf grass is hand pulling Johnsongrass. You can also apply vinegar for a safer herbicide, but it will still burn your lawn if it gets on it.

The most effective way to eliminate quack grass without killing the grass nearby is to overseed the area, keep the seed wet until it grows, mow often, and regularly fertilize the area to promote healthy grass that can choke out the invasive weed.

Mowing is one of the most important ways to maintain your lawn because it encourages grass to grow horizontally, creating a fuller, more uniform yard. On top of mowing your lawn, you’ll want to routinely fertilize your lawn, water it regularly, and take care of pests the moment they arise.