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Glyphosate and other non-selective herbicides can kill orchard grass, but they will also kill the surrounding plants. Also, not all areas allow the use of glyphosate due to its environmental impact—which the EPA describes as a "potential risk to terrestrial and aquatic plants and birds, and low toxicity to honeybees." Consider mechanical removal to target the plants specifically.

The safest method to avoid killing your turf grass is hand pulling Johnsongrass. You can also apply vinegar for a safer herbicide, but it will still burn your lawn if it gets on it.

Mowing a lawn will, unfortunately, not get rid of clover, and it may even encourage it to flourish. Let your lawn grow to a healthy height of over 3 inches and then set your mower blades no lower than this level. Higher grass will cut out the light that clover loves and discourage it from spreading.

Each type of weed comes with its own control methods, but stopping the seed spread is the first step. Grazing, mowing, and hand pulling can slow the invasion. In some cases, selective herbicide is necessary to stop a persistent weed from overtaking an area.