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When you put baking soda and vinegar down the drain, they chemically react and help break down clogs. It’s not going to work for every type of clog, however. For example, it’s not the best way to get rid of grease buildup. For grease, you should try boiling water and white vinegar instead.

Bleach—even diluted bleach—is not always the safest option for cleaning your drains. With a high pH, bleach can be highly corrosive to many types of pipes, especially when used regularly. When mixed with household cleaners and organic waste, it can also create dangerous chemicals. Remember to use proper protective equipment and ventilation when dealing with bleach.

Most commercial liquid drain cleaners work in 15 to 30 minutes. Consult the label on the bottle for additional instructions or time suggestions to prevent damage to your drainpipes. Alternative solutions such as baking soda, salt, white vinegar, and/or boiling water can take longer since they are less harsh than liquid drain cleaners.

If you want to avoid using a snake to unclog a drain, or if you don’t have one, try vinegar and baking soda. Pour 1 cup of baking soda down the drain, followed by 1 cup of white vinegar. Wait for 15 minutes, and then run hot water (but not boiling water) down the drain to see if the clog is clear. Repeat multiple times as needed.