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Whereas a honeybee can only sting you once, a yellow jacket can sting you multiple times because they don’t leave stingers in the skin. In the unfortunate case that you get stung by a yellow jacket, it’s important to react calmly and quickly. Immediately ice the affected area until the swelling subsides. You may also take an antihistamine if necessary. If you experience an allergic reaction to a yellow jacket sting or have been stung several times, seek medical care right away. 

In certain cases, yes, the bees may go away on their own, but it’s a risk. Some bee types, such as bumblebees, create seasonal nests and then die out as their new queens seek homes elsewhere. But in most cases, you can’t count on the bees leaving naturally. It’s also not a great idea to leave openings in your walls any longer than you have to, which can attract other pests or cause moisture damage.

You should never try to remove a bee's nest yourself because it can be extremely dangerous. The amount of bees that can live in a hive depends on the type of bee, but honey bees can have up to 80,000 bees living in a hive. People who are allergic to bees can have life-threatening reactions from a single sting. So, it's best to leave bee nest removal to the professionals who have the knowledge and equipment to do so safely.

Some species of bees (not to mention hornets) are aggressive and dangerous to have in your walls. If they swarm in anger or defense, they could badly hurt people in your home. Other species of bees are largely harmless and many people live in close proximity to them.

Either way, bees making hives in your walls usually causes damage. It can contribute to moisture problems, and attract other pests. Those problems get even worse if honeycombs build up. So we strongly suggest you find a way to keep bees from taking up permanent residence.