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In most cases, drain cleaners will not clear a clogged sewer line, and they’re likely to damage your plumbing. Sewer lines are several inches wide, meaning any material that clogs it will need to be large. Drain cleaner can work on small clogs, but it usually won’t clear a larger one in a sewer main. Drain cleaners can also easily damage and corrode your plumbing with prolonged contact, and a clog will keep the cleaner in contact with the pipes for an extended period. Hire a professional sewer cleaner instead for a safe fix.

Bleach isn’t likely to help unclog a sewer line. Bleach isn’t useful in this situation because it won’t dissolve the grime and debris in the clog. Instead, you want to use ingredients that will have a chemical reaction to clear out the buildup, like vinegar or salt and baking soda.

If you’re wondering whether rats can come up the toilet, the unfortunate answer is yes, it’s possible, though it’s extremely rare. These rodents are excellent swimmers and can travel through sewer pipes in search of food, and they may follow plumbing lines leading to your home if they’re drawn by the scent of scraps and waste. The toilet’s U-bend holds a small pocket of air, which can help a rat catch its breath before making its final push into your bathroom. While more common in cities with larger rat populations, this can happen anywhere with connected sewer systems; sealing entry points and keeping drains clean can help reduce the risk.

No, you should not see water in a sewer cleanout. If you do, it could indicate that you have a block or leak in your main sewer line—which can cause sewage to back up inside your home and potentially flood your yard. Your best bet is to call a local sewer cleaner if you notice any water or sewage around your cleanout.