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There are organic herbicide options that will kill grass but not flowers, including white vinegar or a dish soap solution. Commercial selective herbicides can also target grass over other plants, but read the instructions carefully to avoid damaging your garden. Herbicides that kill grass but not flowers usually include ingredients like clethodim and sethoxydim. Otherwise, your best bet will be to weed by hand.

No, it's not really possible to completely prevent weed growth. Weeds are incredibly resilient—all they usually need is a tiny bit of dirt to sprout, so their eventual appearance is pretty much inevitable. However, you can definitely keep them at bay by getting rid of weeds as soon as you notice them. The longer you let them sit and grow roots, the more they'll spread.

Johnsongrass and crabgrass are invasive weeds that can overtake your lawn. Crabgrass is a low-growing grass most often seen in lawns, flower beds, and vegetable gardens. While you may find Johnsongrass growing in your lawn, it will also grow in pastures, crop fields, and the edge of the road. Johnsongrass is much coarser than crabgrass. If left alone, Johnsongrass can grow up to 8 feet tall. 

Landscaping fabric can only help to prevent weed growth in the short term. It's not an ideal long-term solution because dirt will eventually make its way on top of it, causing weeds to sprout. These fabrics can also leave microplastics in the environment for many, many years, so pulling weeds using one of the methods in this guide as soon as you see them is a better long-term prevention strategy.