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Simply put,  there are much better approaches than using mothballs. Mothballs contain chemicals that can easily permeate a frog's delicate skin, leading to health problems. But it's not limited to just frogs; other animals and the environment could also face negative impacts. The US Environmental Protection Agency (EPA) has taken action. It emphasizes the importance of adhering to label instructions for products like this and not moving forward with off-label use.

Possums are not aggressive toward people or pets. They are shy critters that prefer to avoid confrontations. When threatened, they may hiss, growl, or display their teeth but are more likely to play dead as a defense mechanism. Possums rarely attack unless cornered or provoked. They are not a significant threat to pets, though a curious dog or cat might provoke a defensive reaction.

As with anything ingested by animals, there is always a chance that mushrooms will be toxic. Clearing the tops of mushrooms from the soil to prevent them from being eaten by pets is always a good idea. Since poisonous mushrooms can be deadly, we recommended that any mushroom ingestion is treated as a veterinary emergency. Watch for signs of lethargy and digestive distress in any animal suspected to have eaten a mushroom and contact your vet immediately.

Generally, squirrels are not considered aggressive toward humans. They are more likely to flee than confront people. However, like many animals, they may exhibit aggressive behavior if they feel threatened or cornered. If you approach a squirrel too closely or try to handle it, especially if it's a mother protecting her young, it may resort to defensive tactics such as biting or scratching.