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Weeds can grow through rubber mulch, but it depends on if you removed all the weeds in your garden beforehand. Weeds already in the soil can grow even when using rubber mulch. However, that doesn’t mean that your garden will be littered with rubber and weeds, but it does mean that the occasional weed might still pop up. Another way you can increase your weed suppression is by using landscape fabric as a second layer. 

There are several ways to kill poison ivy permanently. The trick is to keep it from coming back. Herbicides and natural remedies are highly effective for killing existing poison ivy plants. However, plant and root parts left behind can easily create new sprouts that turn into full-grown plants. The only way to permanently get rid of poison ivy is to be patient and diligent until all traces of the plant are dead and gone.

Poison oak is similar to poison ivy in that it's in the same family of plants. Poison oak is identifiable by its rounded-off leaves and hairy leaf texture. Tree-climbing varieties live primarily in western states while low-growing poison oak bushes occupy the eastern states. Treat poison oak like poison ivy to get rid of it permanently.

The best way to prevent weeds is to use polymeric sand, which hardens and blocks weed growth when activated with water. If you're using regular sand, you'll need to refill and compact it more often. Keeping the surface clean and free of debris can also help prevent weed seeds from settling in the joints.