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There are organic herbicide options that will kill grass but not flowers, including white vinegar or a dish soap solution. Commercial selective herbicides can also target grass over other plants, but read the instructions carefully to avoid damaging your garden. Herbicides that kill grass but not flowers usually include ingredients like clethodim and sethoxydim. Otherwise, your best bet will be to weed by hand.

Ultimately, pulling weeds vs. spraying them depends on what’s happening in your yard and your personal preferences. Manual weed removal doesn’t introduce any chemicals into your landscape, targets specific problematic plants, produces immediate results, can be free if you go the DIY route, and is inexpensive with a weed service if you only have a handful of weeds. On the other hand, spraying is often preferable for severe weed infestations and situations involving difficult-to-pull weeds because it treats multiple weeds at once, is usually more effective long-term, is less time-consuming, and costs less when done by a pro.

The best time to fight crabgrass with pre-emergent herbicide is when forsythias tend to bloom. In the mid-Atlantic region, this is usually between April and May. Even if you're late to apply the herbicide, it’s effective as long as the crabgrass plant has fewer than five leaves.

Purchase a selective herbicide that targets clover and similar weeds but doesn't take out your grass. You can also keep it from growing with corn meal gluten or remove clover from your lawn manually at the start of the season as part of your lawn maintenance checklist.