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Vinegar is known to be a contact herbicide, which means it kills the foliage it comes in contact with. Because of the high acetic acid concentration, horticultural vinegar kills weeds and grass more effectively. However, keep in mind that high amounts and multiple applications can affect the soil by lowering the pH levels.

You should add 1 to 4 inches of mulch, depending on your garden type and needs. Keep in mind that no amount of mulch can completely prevent weeds, but a heavier coverage (closer to 4 inches) can suppress weeds enough that you are only seeing them sprout every few weeks. Finer mulch prevents weeds more effectively than large mulch, so if you’re using mulched leaves or shredded bark, 1 to 2 inches will likely suffice, while 3 to 4 inches is best for larger mulch, like bark chips or straw.

There are many options to eradicate weeds right down to the roots. Vinegar works, but it takes a week or so to do its thing, and the same goes for many commercially available herbicides. Boiled water is a quick way to kill off roots, or you can pull up weeds at the root.

Pulling weeds once per month is typically often enough to keep most weeds at bay. But in general, it's best to pull weeds as soon as you spot them to prevent deep root growth and slow their spread. To make it easier, plan your weed pulling after rain or after the sprinklers run so the soil will be nice and wet and the weeds will be easier to pull. If you notice moss accompanying weeds, make a plan to remove the moss immediately to prevent damage.