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Ultimately, pulling weeds vs. spraying them depends on what’s happening in your yard and your personal preferences. Manual weed removal doesn’t introduce any chemicals into your landscape, targets specific problematic plants, produces immediate results, can be free if you go the DIY route, and is inexpensive with a weed service if you only have a handful of weeds. On the other hand, spraying is often preferable for severe weed infestations and situations involving difficult-to-pull weeds because it treats multiple weeds at once, is usually more effective long-term, is less time-consuming, and costs less when done by a pro.

If you have a lot of tree roots in your yard or have experienced issues in the past, you should use tree root killer every six months to prevent roots from infiltrating your pipes. If you have an active invasion and aren’t seeing results, check the instructions on the bottle to see how often you can use it in a short period of mine.

Glyphosate and other non-selective herbicides can kill orchard grass, but they will also kill the surrounding plants. Also, not all areas allow the use of glyphosate due to its environmental impact—which the EPA describes as a "potential risk to terrestrial and aquatic plants and birds, and low toxicity to honeybees." Consider mechanical removal to target the plants specifically.

The main problem with crabgrass is that it produces thousands of seeds that can remain dormant until the following season. To get rid of it, you have to remove existing plants before they have a chance to spread seeds and stop old seeds from germinating.