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Purchase a selective herbicide that targets clover and similar weeds but doesn't take out your grass. You can also keep it from growing with corn meal gluten or remove clover from your lawn manually at the start of the season as part of your lawn maintenance checklist.

Buffalo grass is not a dense grass, so weeds can grow between the buffalo grass plants. However, as long as you don’t overwater your lawn, weeds have a hard time growing. If you do notice weeds, you can use granular herbicides that are safe for buffalo grass in early and late summer.

Pulling weeds once per month is typically often enough to keep most weeds at bay. But in general, it's best to pull weeds as soon as you spot them to prevent deep root growth and slow their spread. To make it easier, plan your weed pulling after rain or after the sprinklers run so the soil will be nice and wet and the weeds will be easier to pull. If you notice moss accompanying weeds, make a plan to remove the moss immediately to prevent damage.

There are many options to eradicate weeds right down to the roots. Vinegar works, but it takes a week or so to do its thing, and the same goes for many commercially available herbicides. Boiled water is a quick way to kill off roots, or you can pull up weeds at the root.