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Squirrels hate not having access to secure shelter or food sources. Your best line of defense is to make your property less attractive by removing access to these things. There are chemical squirrel repellents, but these have mixed success. According to Pennsylvania State University, you can apply products containing the bittering agent denatonium saccharide to a squirrel's favorite fence, tree, or roof spots. However, you need to reapply repellents regularly, which aren’t scientifically proven effective.

Besides reptile sightings, look for droppings resembling small pellets. Shed skin left behind during growth is another clue. Unusual chirping or rustling sounds could also suggest an infestation. If unsure, consulting a professional can provide accurate identification and effective solutions for managing the situation. If proper pest prevention measures aren't taken, a lizard can live up to five years. And that's a long time to have an undesirable roommate.

Some snake repellents are risky to use around people and pets because they use the active ingredient in mothballs, naphthalene. The United States Environmental Protection Agency (EPA) has classified naphthalene as a carcinogen that can cause damage to the liver, neurological issues, and cataracts. 

The Colorado State University Extension suggests there’s not enough conclusive evidence of the effectiveness of snake repellents to recommend their use.

How long skunks stick around depends on the time of year and whether they have youngsters. Skunks only spend a few days in a den during warm months. However, they’ll put down roots during the other seasons, particularly females with kits. Female skunks may stay in the same place throughout early spring and summer, and all skunks usually stick around during the winter months. No matter the season, skunks prefer safe areas with plenty of access to food.