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The last thing you want is to fend off a swarm while on top of a fully-extended ladder. Additionally, be extremely careful when using a ladder, as falling from a tall height can result in serious injury. 

Leaving things to a pest control service in your area could be the best course of action if the nest is in an enclosed or difficult-to-reach space. If your spray doesn’t hit the right spot, is too far away, or isn’t powerful enough, you risk aggravating rather than killing all the wasps.

Squirrels hate not having access to secure shelter or food sources. Your best line of defense is to make your property less attractive by removing access to these things. There are chemical squirrel repellents, but these have mixed success. According to Pennsylvania State University, you can apply products containing the bittering agent denatonium saccharide to a squirrel's favorite fence, tree, or roof spots. However, you need to reapply repellents regularly, which aren’t scientifically proven effective.

Clean your drains with either a bleach solution or a mixture of apple cider vinegar, baking soda, and boiling water. Repeat the process several times in one week to ensure you've killed the whole nest.

Boric acid is among the harsher chemicals you can use in your home, and it poses risks whether ingested, inhaled, or touched. Kids and pets alike tend to put their hands and mouths on anything within reach, so it’s always a good idea to store boric acid in a spot they can’t get to and use it only when they’re not around for an extended period. When you use it, ensure they’re out of the house and fully clean up any trace of boric acid when you’re done because even a small amount can cause problems.