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Droppings from cockroaches, squirrels, mice, bats, and birds can resemble rat poop, making it easy to confuse one for another. Mouse droppings are smaller and more pointed, cockroach droppings resemble tiny black specks or ground pepper, and bat guano can look similar but usually crumbles into powder. Bird droppings sometimes have a similar shape, but often include white uric acid deposits. If in doubt, it’s best to consult a pest control professional for proper identification and removal.

While possums don’t typically carry rabies, they can have lice, fleas, ticks, and mites. According to the University of California’s Pest Management Program, possums can also carry diseases like leptospirosis, tuberculosis, toxoplasmosis, coccidiosis, and fevers. Possums are also the carriers of a parasite that can pass to horses and cats called Equine Protozoal Myeloencephalitis (EPM).

Groundhogs are non-aggressive animals that are afraid of humans. They forage for vegetation in yards and gardens, so they can often be seen as a nuisance if you spot one on your property. That said, if you happen to get bitten or scratched by a fearful groundhog, be sure to get checked by a doctor, as they could carry infections or diseases like rabies, Lyme, or the rare tularemia.

DIY animal removal is rarely a good idea and is not advised for many reasons. First, these types of animals can carry diseases and, therefore, pose a health risk to you, your family, and your pets if mishandled. Second, depending on your city or municipality, it may be illegal to remove or handle wildlife yourself. 

Sealing your home against these animals yourself is also a bad idea. Trapping an animal under your house will cause odor and insect problems when it passes away.