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The best way to prevent weeds is to use polymeric sand, which hardens and blocks weed growth when activated with water. If you're using regular sand, you'll need to refill and compact it more often. Keeping the surface clean and free of debris can also help prevent weed seeds from settling in the joints.

Johnsongrass and crabgrass are invasive weeds that can overtake your lawn. Crabgrass is a low-growing grass most often seen in lawns, flower beds, and vegetable gardens. While you may find Johnsongrass growing in your lawn, it will also grow in pastures, crop fields, and the edge of the road. Johnsongrass is much coarser than crabgrass. If left alone, Johnsongrass can grow up to 8 feet tall. 

Vinegar cannot tell the difference between weeds and desired grass types; it kills everything it touches. Only use a vinegar or vinegar-based solution if you are relatively confident that you can navigate around the plants and grasses you want to keep. Also, don’t spray vinegar on a windy day, or it will blow onto other plants.

Crabgrass is very resilient, and homemade solutions like vinegar may not be strong enough. Typically, hand-weeding is the most effective option that doesn’t involve harmful chemicals. You can use corn-meal gluten as a natural pre-emergent herbicide, but it’s not as effective as chemical weed killers.