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Anything that might have been exposed to fumigation chemicals should be washed before use. Wipe down and sanitize surfaces like countertops and tables, and wash all utensils (or take care to store them in an airtight box beforehand), as well as anything else that could find its way into someone’s mouth, like kid or pet toys. 

You can clean some mattresses with a carpet cleaner that has an upholstery attachment. Mattresses made out of memory foam or other foam generally should not be cleaned with a carpet cleaner, although many traditional spring mattresses can be cleaned this way. Consult the manufacturer’s instructions to be sure. If you do use a carpet cleaner, be aware that it will take much longer to fully dry and be careful not to oversaturate the mattress.

Leaving pee on a mattress for an extended period of time will make it harder to remove the moisture, increase the likelihood of unappealing stains forming, and make the urine odor linger for a longer time. Ideally, you should start cleaning a urine-soaked mattress immediately. You can start by spraying a 1:1 solution of white distilled vinegar and water over the stain and then blotting it out. Then, sprinkle baking soda over the affected area, let it sit for 8 to 10 hours, and then vacuum it out. If the issue persists, you might need to dispose of your mattress and replace it.

Over time, a urine-soaked mattress will lose the pee odor on its own as long as it dries out completely. However, it’s best to help the process along either by calling in a professional mattress cleaner or by using household cleaning products like white distilled vinegar and baking soda to remove the moisture and the odor. You may want to consider replacing your mattress over cleaning it if you have multiple stains or odors that are persistent.