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Vinegar is known to be a contact herbicide, which means it kills the foliage it comes in contact with. Because of the high acetic acid concentration, horticultural vinegar kills weeds and grass more effectively. However, keep in mind that high amounts and multiple applications can affect the soil by lowering the pH levels.

If you have a lot of tree roots in your yard or have experienced issues in the past, you should use tree root killer every six months to prevent roots from infiltrating your pipes. If you have an active invasion and aren’t seeing results, check the instructions on the bottle to see how often you can use it in a short period of mine.

The best way to prevent weeds is to use polymeric sand, which hardens and blocks weed growth when activated with water. If you're using regular sand, you'll need to refill and compact it more often. Keeping the surface clean and free of debris can also help prevent weed seeds from settling in the joints.

Crabgrass is very resilient, and homemade solutions like vinegar may not be strong enough. Typically, hand-weeding is the most effective option that doesn’t involve harmful chemicals. You can use corn-meal gluten as a natural pre-emergent herbicide, but it’s not as effective as chemical weed killers.