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Generally, squirrels are not considered aggressive toward humans. They are more likely to flee than confront people. However, like many animals, they may exhibit aggressive behavior if they feel threatened or cornered. If you approach a squirrel too closely or try to handle it, especially if it's a mother protecting her young, it may resort to defensive tactics such as biting or scratching.

This varies based on the circumstance. Chemical-based pest control baits and poisons are usually the most potent, but they are unsafe to use around children and pets, so they won’t be a fit for every household.

Safer alternatives, such as boric acid and food-grade diatomaceous earth, can work as well, though they should still stay out of reach. Aside from that, the best thing any DIY-er can do is make their place uninviting by sealing off entry points, eliminating clutter, and maintaining a clean home.

Like many other rodents, squirrels can be a little difficult to get rid of (especially in the case of an infestation), but the best approach is to make the place as unattractive to squirrels as possible. If you do have an infestation inside your home, then professional help may be necessary so you can lay as many traps as possible. 

You know if you have a skunk hole if you can smell the skunk’s musk. Skunks have a strong odor even when they aren’t spraying due to threats, and you may smell it coming from under a building or another hiding spot, such as a shrub or wood pile. They may also dig shallow holes around a lawn in search of food.