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You can use baking soda to start getting the urine odor out of your mattress. Baking soda is highly absorbent and soaks up odors, so it will not only draw the urine out of your mattress but it can also get to work fighting the lingering smell. You can also use an enzymatic cleaner to break down the urine to make it easier to clean. Just keep in mind that you need to remove enzymatic cleaners from the mattress after use, as leaving them on could be dangerous.

To maintain your mattress and keep it fresh, you should aim for a deep clean at least twice a year. However, if you have allergies, pets, or sweat heavily at night, you may want to clean it more frequently, such as every three to four months. In between deep cleanings, it's a good practice to vacuum the mattress surface regularly and spot-clean any stains as they occur. Using a mattress protector can significantly help by minimizing the buildup of allergens, dust mites, and bodily fluids, which can make your cleaning routine more effective. Remember to launder the protector regularly, as some dirt and sweat can still get through to the mattress.

If you don’t have the time or ability to move your fridge, grab a yardstick and slide it underneath to unearth any large items and dust bunnies. Then, attach a microfiber cloth or a tube sock to the yardstick, spray it with a multipurpose cleaner, and sweep it around several times to pick up any lingering messes.

Various mites can cause health problems for people and pets, such as allergies, skin irritation, and respiratory issues. Some mites, like scabies and chiggers, can transmit diseases or bacterial infections. Other types, such as dust, mold, and spider mites, also pose risks. Spider mites, for example, can quickly spread to and damage houseplants. It is best to eradicate any type of mite from your home and seek medical care if you experience symptoms.