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Buffalo grass is not a dense grass, so weeds can grow between the buffalo grass plants. However, as long as you don’t overwater your lawn, weeds have a hard time growing. If you do notice weeds, you can use granular herbicides that are safe for buffalo grass in early and late summer.

Pulling weeds once per month is typically often enough to keep most weeds at bay. But in general, it's best to pull weeds as soon as you spot them to prevent deep root growth and slow their spread. To make it easier, plan your weed pulling after rain or after the sprinklers run so the soil will be nice and wet and the weeds will be easier to pull. If you notice moss accompanying weeds, make a plan to remove the moss immediately to prevent damage.

Crabgrass is very resilient, and homemade solutions like vinegar may not be strong enough. Typically, hand-weeding is the most effective option that doesn’t involve harmful chemicals. You can use corn-meal gluten as a natural pre-emergent herbicide, but it’s not as effective as chemical weed killers.

Weed control applications usually cost around $100 each for a standard-size yard, and most professionals charge between $30 and $60 per hour for manual weed removal. Your total is affected most by the size of the weeded area. Some weed service companies offer weed control treatments, selective herbicide spraying, and manual removal and upkeep as part of a package, costing around $600 annually. You might pay less if you hire the same company for other lawn services, like flower bed upkeep, aeration, overseeding, and pesticide application.