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No, it is not advisable to spray pesticides down the drain in your home. Most drinking water and wastewater treatment systems are not properly equipped to remove pesticides. Should pesticides infiltrate waterways, they can cause harm to plants, fish, or other living things. In most areas, pouring pesticides down the drain is illegal due to the potential harm it causes. 

Some homeowners use additives every month to help septic system performance, but according to the U.S. Environmental Protection Agency, the effectiveness of septic system and leach field additives is unknown. Further, additives made with organic solvents or alkali chemicals can actually be harmful to the necessary bacteria in a septic system.

Bleach is generally not recommended for your shower drains. Although diluted bleach can technically help clean your drain, it will not unclog your pipes. In fact, bleach can harm your plumbing system because it’s so powerful. The bleach can change the color of your sink and even corrode metal pipes and fittings.

Often, people reach for bleach because it's already in their house. But it's worth getting a plunger or a drain snake for the job instead. It'll be a lot less money to buy a new plunger than to pay a plumber to repair or replace damaged pipes.

Your sewer line can get grimy quickly. To prevent sludge buildup in your sewer line, pour a mixture of 1/3 cup of vinegar and 1/3 cup of baking soda down each drain in your home once a month. After about 30 minutes, flush the drain with hot water.

Some plumbers recommend 3/4 cup of bleach instead to clean any germs and bacteria that may build up in your sewer line. But this won’t break down any active clogs, and it cannot be combined with vinegar, as the mixture will create a toxic, hazardous gas.