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No, it's not really possible to completely prevent weed growth. Weeds are incredibly resilient—all they usually need is a tiny bit of dirt to sprout, so their eventual appearance is pretty much inevitable. However, you can definitely keep them at bay by getting rid of weeds as soon as you notice them. The longer you let them sit and grow roots, the more they'll spread.

Mowing your grass regularly, especially if you’re mowing close to the ground, can help kill Johnsongrass. Frequent mowing helps limit the spread of Johnsongrass and can even deplete carbohydrate reserves in rhizomes over time. The more time you leave in between mowing, the more likely Johnsongrass is to regrow and take over your lawn. 

Herbicides containing a combination of the active chemical ingredients dicamba, fluroxpyr, and quinclorac are most effective at purging your turf of white clover. However, for small home lawns, organic prevention and control can be very effective methods for killing clover weeds and save you from using harmful pesticides that might damage your lawn.

Yes, vinegar can be an effective way to kill individual dandelion plants to help in the hand-removal process. However, vinegar can also kill turfgrass, so use a targeted spray.