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The most effective way to eliminate quack grass without killing the grass nearby is to overseed the area, keep the seed wet until it grows, mow often, and regularly fertilize the area to promote healthy grass that can choke out the invasive weed.

If possible, you should prioritize pulling weeds up by hand. However, be sure not to use your bare hands, as many weeds are sharp or otherwise irritating when they come in contact with skin. Always don thick, protective gardening gloves to protect your hands when you pull up weeds.

The best time to fight crabgrass with pre-emergent herbicide is when forsythias tend to bloom. In the mid-Atlantic region, this is usually between April and May. Even if you're late to apply the herbicide, it’s effective as long as the crabgrass plant has fewer than five leaves.

If you have a lot of tree roots in your yard or have experienced issues in the past, you should use tree root killer every six months to prevent roots from infiltrating your pipes. If you have an active invasion and aren’t seeing results, check the instructions on the bottle to see how often you can use it in a short period of mine.